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What is best practice for managing upper limb spasticity following stroke in occupational therapy?

AI Synthesis6 sources reviewed

Upper limb spasticity following stroke is best managed through a multimodal approach combining botulinum toxin A (BoNT-A) injections with structured occupational therapy goal-directed training.

Evidence Summary (Evidence Grade: A, Systematic Review)

A 2023 Cochrane systematic review (Hayward et al.) found BoNT-A combined with goal-directed rehabilitation significantly reduced spasticity (Modified Ashworth Scale MD −0.8, 95% CI −1.1 to −0.5) and improved upper limb function compared to BoNT-A alone. Splinting and positioning are recommended as adjuncts but should not replace active movement practice. Electrical stimulation (NMES/FES) shows moderate evidence for reducing spasticity when combined with task-specific training.

Key Recommendations

• BoNT-A + goal-directed OT (Grade A): first-line combination therapy • Constraint-Induced Movement Therapy (Grade A): for eligible patients with retained wrist/finger extension • NMES/FES (Grade B): as adjunct to active practice • Prolonged stretch/splinting (Grade C): for prevention of contracture only

Citations

Level I

Botulinum toxin for upper limb spasticity following stroke

Hayward KS et al. (2023) · Systematic Review / Meta-analysis

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Level I

Constraint-induced movement therapy for upper extremities in people with stroke

Corbetta D et al. (2015) · Systematic Review / Meta-analysis

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Level II

Functional electrical stimulation for improving motor recovery after stroke

Howlett OA et al. (2015) · Systematic Review / Meta-analysis